Study the Clinical and Electrocardiographic Changes in Organophosphorus Poisoning

DOI: 10.21276/sjams.2017.5.9.47 Abstract: OP compound poisoning is a global problem and is most common medicotoxic emergency in India. Cardiac manifestations are also seen due to OP poisoning which may be serious and often fatal if not diagnosed early and treated adequately. We studied clinical and electrocardiographic changes in op poisoning. To study the clinical as well as electrocardiographic changes in patients with Organophosphorus compound poisoning. A total of 95 patients were included in the study. Patients admitted to tertiary care center with history of OP poisoning, with clinical symptoms and signs in less than 24hrs were included in the study. Electrocardiogram was done on day of admission, 3 rd day and 7 th day. In our study (51.6%) were female, 48.4 % were male. Incidence of OP poisoning was more common among age group 21-30 years. Farmers (35.8%) were more common among occupation. Monocrotophos (25.3%) was commonly used compound for poisoning. The commonest clinical findings noted were increased secretions (vomiting, urination, sweating) followed by signs such as mitosis and fasciculation’s. Study also revealed significant electrocardiographic changes associated with OP poisoning during hospitalization and reverted during discharge by 7 th day. Common electrocardiographic changes in patients with organophosphorus compound poisoning noticed were sinus tachycardia, sinus bradycardia, prolonged QTc, ST-T changes like ST inversion and T inversion and Tall T. Electrocardiogram changes can also be used as a prognostic tool.